Expanded access to naloxone: options for critical response to the epidemic of opioid overdose mortality.
For more than three decades, naloxone has been used by emergency medical personnel to reverse overdoses. However, friends or family members are most often the actual first responders and are best positioned to intervene within an hour of the onset of overdose symptoms. Current evidence supports the extensive scaleup of access to naloxone. This article presents advantages and limitations associated with a range of possible policy and program responses.